Ibuprofen Basic Information

Product Name: Ibuprofen

CAS: 15687-27-1

MF:  C13H18O2

MW: 206.28

EINECS: 239-784-6

Ibuprofen Chemical Properties

Melting point: 77-78 °C(lit.)

Boiling point: 157 °C (4 mmHg)

Density: 1.0364 (rough estimate)

Refractive index: 1.5500 (estimate)

Storage temp.: -20℃ Freezer

Solubility: Practically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.

Form: Crystalline Powder

Color: White to off-white

Water Solubility: Insoluble

Application:

Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 values of 13 μM and 370 μM, respectively, and has anti-inflammatory activity.

1. Alleviate acute exacerbation or persistent joint swelling and pain symptoms of various chronic arthritis such as rheumatoid arthritis, osteoarthritis, spondyloarthropathy, gouty arthritis, rheumatoid arthritis, no cause of disease treatment and disease control The role.

2. treatment of non-articular soft tissue rheumatic pain, such as shoulder pain, tenosynovitis, bursitis, myalgia and post-exercise injury pain.

3. acute mild to moderate pain such as: after surgery, post-traumatic, strain, primary dysmenorrhea, toothache, headache and so on.

4. It has antipyretic effect on fever in adults and children.